October 24, 2021

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6 Best Vitamin C Serums of 2021 [Dermatologist Approved]

From eating foods for healthy skin to switching up your morning and routines, taking care of the largest organ in the body can get overwhelming. Recently, vitamin C has grown in popularity in the skincare world — but do the best vitamin C serums live up to the hype?

Vitamin C is not only an essential supplement for your immune system and overall health, but it’s also a great skincare ingredient that can help limit inflammation, brighten skin, dull fine lines and wrinkles, fight free radicals, and reduce discoloration and dark spots.

Adding vitamin C to your skincare routine seems like a no-brainer, but before you start shopping for a serum, it’s important to be aware that vitamin C is an unstable ingredient. Dermatologists say it’s important to find legit and properly formulated vitamin C serums to capitalize on the benefits of the antioxidant. In this article, we’ll help you find the right dermatologist-approved vitamin C serum to add to your routine.


Our Picks for the Best Vitamin C Serums of 2021

Each product featured here has been independently selected by the writer. You can learn more about our review methodology here. If you make a purchase using the links included, we may earn commission.

Skincare Benefits of Vitamin C

Also known as ascorbic acid or L-ascorbic acid, vitamin C is an antioxidant that is present in the formation of collagen and that protects against aging, according to Dr. Anna Chacon, a board-certified dermatologist with MyPsoriasisTeam. A vitamin C serum may be a solid addition to your skincare routine because it has a great safety profile, and it’s safe for most skin types.

“Vitamin C serum restores and neutralizes environmental stressors that accelerate signs of aging and can be used morning and evening,” Dr. Chacon says. However, she warns, “it does not come with sun protection, so additional use of sunscreen is recommended.”

As an antioxidant, vitamin C protects skin cells from being damaged by free radicals from things like UV exposure, vehicle exhaust and cigarette smoke. It also hampers melanin production, which can help to lighten hyperpigmentation and brown spots and even out your skin tone.

6 Best Vitamin C Serums

Based on dermatologist recommendations and our market research, the following products are the best vitamin C serums available today.

Best Overall: ZO Skin Health 10% Vitamin C Self-Activating

zoskinhealth.com

Our overall recommendation for the best vitamin C serum is the ZO Skin Health 10% Vitamin C Self-Activating serum. The product contains 10% vitamin C, which has anti-aging properties and minimizes the appearance of fine lines, wrinkles and sunspots by promoting collagen production. “I have this in my bathroom,” Dr. Chacon says. “It is gentle and non-irritating, and it leaves your skin radiant afterward.”

Customer Rating: 4.7 out of 5 stars with under 100 Amazon ratings

Why Buy: Along with L-ascorbic acid, this serum includes ingredients like Coenzyme Q10 for multi-layer antioxidant protection and plant-derived squalane for added hydration. ZO Skin Health’s products are all cruelty-free.

Best for Sensitive Skin: Paula’s Choice RESIST Super Antioxidant Concentrate Serum

Paula's Choice RESIST Super Antioxidant Concentrate Serum

paulaschoice.com

Made with plant- and vitamin-derived antioxidants including vitamin C, vitamin E, peptides and CoQ10, Paula’s Choice RESIST Super Antioxidant Concentrate Serum will help rejuvenate your skin. The formula fights dullness, enhances firmness and reduces the appearance of wrinkles.

Customer Rating: 4.6 out of 5 stars with about 300 Amazon ratings

Why Buy: This product is paraben-free, fragrance-free and cruelty-free, as it’s not tested on animals. The container is 100% recyclable through TerraCycle, and it’s formulated and manufactured in the U.S.

Best Budget-Friendly Serum: CeraVe Vitamin C Serum with Hyaluronic Acid

CeraVe Vitamin C Serum with Hyaluronic Acid

cerave.com

CeraVe Vitamin C Serum with Hyaluronic Acid offers high value at a reasonable price. It is a hydrating vitamin C serum that’s fragrance-free, paraben-free, non-comedogenic and budget-friendly to boot. The formula uses 10% pure vitamin C to prevent free radical damage as well as soothing vitamin B5 and hyaluronic acid to make the skin look smooth and create a moisture barrier for your skin.

Customer Rating: 4.5 out of 5 stars with over 20,000 Amazon ratings

Why Buy: Chacon calls CeraVe “a trusted, dermatologist-oriented brand” that comes at drugstore prices, so it’s a great choice if you want to try out a budget-friendly vitamin C serum.

Best Cruelty-Free Serum: Timeless Skin Care 20% Vitamin C Plus E Ferulic Acid Serum

Timeless Skin Care 20% Vitamin C Plus E Ferulic Acid Serum

timelessha.com

Timeless Skin Care’s vitamin C serum promotes healthy cell turnover to help minimize the effects of hyperpigmentation and even out your skin tone. According to Dr. Chacon, “vitamin C, E and ferulic acid are all key ingredients that help to brighten skin, building up collagen and evening out tone.” This product’s formula is non-greasy and lightweight, so it absorbs quickly and clearly into the skin.

Customer Rating: 4.3 out of 5 stars with over 1,700 Amazon ratings

Why Buy: The Timeless Skin Care formula is paraben-free, synthetic dye-free, fragrance-free and polyethylene glycol-free. The company doesn’t test on animals, and the product is made in the U.S. from natural ingredients. It’s also part of the TerraCycle recycling program.

Best Anti-Aging Serum: SkinCeuticals C E Ferulic Combination Antioxidant Treatment

SkinCeuticals C E Ferulic Combination Antioxidant Treatment

skinceuticals.com

Using dermatologist-approved ingredients, SkinCeuticals C E Ferulic Combination Antioxidant Treatment is lightweight and helps to firm, smooth, and brighten the skin for a more youthful look. The formula utilizes 15% pure vitamin C as well as vitamin E and ferulic acid to protect against environmental damage from things like sunlight, ozone pollution and diesel engine exhaust. Plus, it helps firm the skin and reduce the appearance of wrinkles and fine lines.

Customer Rating: 4.1 out of 5 stars with over 200 Amazon ratings

Why Buy: The SkinCeuticals C E Ferulic Combination Antioxidant Treatment is one of the best vitamin C serums for anti-aging purposes. It has an oil-like formulation that goes on smoothly and works effectively without clogging pores.

Best Brightening Serum: The Ordinary Vitamin C Suspension 23% + HA Spheres 2%

The Ordinary Vitamin C Suspension 23% + HA Spheres 2%

theordinary.deciem.com

The Ordinary Vitamin C Suspension 23% + HA Spheres 2% is a topical form of vitamin C that’s rich in antioxidants to target aging and brighten the skin. It uses a high concentration of L-ascorbic acid as well as hyaluronic acid spheres for skin hydration. The brightening serum helps enhance skin smoothness and radiance without being too harsh. However, to test skin sensitivity, it is always recommended to perform a patch test before a full application.

Customer Rating: 4.3 out of 5 stars with over 4,500 Amazon ratings

Why Buy: This vitamin C brightening serum is cruelty-free and vegan and does not contain alcohol, phthalates, gluten, fragrance, nuts, oil, silicone, parabens or sulfates. The moisturizing serum is good for all skin types, including acne-prone skin and dry skin.

FAQ: Best Vitamin C Serums

What vitamin C serum is the most effective?

Our top recommended vitamin C serum is the ZO Skin Health 10% Vitamin C Self-Activating serum. It is a dermatologist-approved antioxidant powerhouse, yet it is gentle, non-irritating and leaves you with glowing skin.

Should you use vitamin C serum every day?

Dermatologists recommend using vitamin C serum either every day or every other day. After you cleanse and tone your face, use your vitamin c product before applying moisturizer and reef-safe sunscreen with at least SPF 30.

Does vitamin C serum really work?

According to dermatologists, the best vitamin C serums work to protect against skin aging. However, if you do not purchase a doctor-recommended product, you run the risk of wasting your money on a low-concentration serum that won’t give you any benefits.

What are the drawbacks of vitamin C serums?

Many vitamin C serums on the market, especially cheaper products, have nearly immeasurable concentrations of antioxidants, which makes them ineffective. Additionally, as with any skincare product, some individuals may have reactions to vitamin C serums including itchiness and redness.

Anna H. Chacon, M.D. is a dermatologist and author originally from Miami, Florida. She has authored over a dozen peer-reviewed articles, book chapters and has been published in JAAD, Archives of Dermatology, British Journal of Dermatology, Cosmetic Dermatology and Cutis.


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